Present experiments were undertaken in order to clarify the clinico-pathological characteristics of lead poisoning in goats. Twenty goats were divided into three experimental groups(A, B and C) and a control(D). The three experimental groups received diets contaminated artificially with 10(A group), Z00(B group) and 1,000(C group) ㎍/ of lead, for 70 days respectively. The control group received normal diets. Blood samples were collected 1 or 2 weeks interval and were examined for anemia(erythrocyte counts, hemoglobin concentrations and hematocrit values) and lead contents of erythrocyte and serum.
Urine samples collected similarly with blood were examined for delta-aminolevulinic acid and lead content. Collected samples were analyzed for lead content by atomic absorption spectrophotometry.
From these experiments following results were obtained : In group B and C, marked decreases in body weight and feed intake, and diarrhea were observed from the 30^(th) day of experimental periods.
The B and C groups showed pronounced anemia(decrease in erythrocyte count, hemoglobin concentration and hematocrit value) from the 21^(st) or 42^(nd) day.
In group B and C, the lead content of erythrocytes was increased significantly from the 28^(th) or 14^(th) day.
The lead content of serum was increased significantly from the 42^(nd) or 14^(th) day in B and C groups.
The lead content of urine was increased significantly from the first day in both B and C groups.
The urinary delta-aminolevulinic acid content was increased significantly from 14^(th) day in both B and C groups.
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